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New Developments Give Fat Transfer Injectables Longer-Lasting Results

Improved Fat Transfer Results

An article in Cosmetic Surgery Times recently reported that the use of a new matrix known as Selphyl in the fat grafting process was found to improve the effectiveness and results of the procedure in a recent clinical study.

The crucial development in this procedure shows that the addition of a matrix known as Selphyl to the fat transfer helps grow more blood vessels in the injection area. The additional growth of these blood vessels makes the fat transfer process more effective by allowing the fat to survive longer. This leads to longer-lasting results with a decreased need for revisionary procedures.

Selphyl Matrix Gives Longer-Lasting Fat Grafting Results


The fat grafting procedure has proven to be highly effective due to its use of natural body fat as a facial filler. By the utilization of a natural body substance, the chance of rejection is eliminated and the likelihood of infection is greatly reduced over other facial injectables.

The fat grafting process involves the removal of fat from trouble areas using liposuction. This removed fat is then purified and processed to create a filler that is easily accepted by the body. This filler is then injected into the target facial areas at specific depths and locations to fill out sunken areas of the face.

One of the few drawbacks of this procedure is the variability of the injected fat cell survival. Typically 30-50% of the fat injected is absorbed by the body, necessitating overfill in order to compensate for the expected loss. The introduction of Selphyl into the fat grafting procedure helps decrease the absorption and make the procedure more consistent. This makes fat grafting easier to plan for without unnecessary overfilling.

The Selphyl matrix is injected as a 1:2 mixture with the harvested fat cells. Selphyl is made up of a biocompatible platelet-rich fibrin matrix that has been shown to increase neovascularization and total cell number. Fat grafting may be used in conjunction with a variety of procedures, including facelifts and hand rejuvenation surgery.

The study was reported in the American Journal of Cosmetic Surgery.
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